Bill and Melinda Gates Foundation: Grand Challenges Explorations

Grand Challenges Explorations will foster early-stage innovation in global health research and expand the pipeline of ideas that merit further exploration. The program will employ a new, fast-track approach to grant making, with short two-page applications and no preliminary data required. Each round of the Grand Challenges Explorations initiative will award grants against a set of specific topics. In general, topics are chosen according to three major criteria: (1) The topic fits within the goals and disease priorities of the Grand Challenges in Global Health; (2) The topic contains a roadblock where radical, new thinking is needed for the discovery of an effective health solution; (3) Potential projects within the topic are likely to be well suited for the phased structure of the initiative. In addition, we consider whether a topic will engage the participation from scientists outside traditional global health disciplines, as well as researchers working in the developing world.

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