Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Smock discusses the "new American family" on NPR

Pfeffer and colleagues re-examine impacts of community college attendance

Frey explains the minority-majority remapping of America

Highlights

Apply for 2-year NICHD Postdoctoral Fellowships that begin September 2015

PSC Fall 2014 Newsletter now available

Martha Bailey and Nicolas Duquette win Cole Prize for article on War on Poverty

Michigan's graduate sociology program tied for 4th with Stanford in USN&WR rankings

Next Brown Bag

Monday, Dec 1
Linda Waite, Health & Well-Being of Adults over 60

Sudden Death and Myocardial Infarction in First Degree Relatives as Predictors of Primary Cardiac Arrest

Publication Abstract

Friedlander, Y., D.S. Siscovick, P. Arbogast, B.M. Psaty, S. Weinman, R.N. Lemaitre, Trivellore Raghunathan, and L.A. Cobb. 2002. "Sudden Death and Myocardial Infarction in First Degree Relatives as Predictors of Primary Cardiac Arrest." Atherosclerosis, 162:211-216.

The hypothesis that family history (FH) of myocardial infarction (MI) and FH of sudden death (SD) are both independent risk factors for primary cardiac arrest (PCA) was examined in a case-control study. PCA cases were attended by paramedics (1988-1994) and community-based age and sex matched controls were identified. Subjects (125-74 years) were free of prior clinically-recognized heart disease and major co-morbidity. Interviewers obtained a detailed history of MI and SD in first-degree relatives from Spouses of 235 cases and 374 control subjects. A parental history of early-onset SD (age < 65) was associated with an increased risk of PCA (odds ratio (OR) = 2.69, 95%, CI = 1.35-5.36), after adjustment for parental history of MI and other risk factors. A parental history of late-onset SD was not associated with PCA risk (OR = 0.94, 95% CI = 0.55-1.62). Additionally, parental history of SD was related to early-onset PCA (OR = 1.89 95%, CI = 1.08-3.30) but not to late-onset PCA (OR = 0.89, 95% CI = 0.49-1.61). In contrast, parental MI (early/late) was related to PCA (early late), after adjustment for other risk factors and parental history of SD. Similar results were observed in first-degree relatives. Findings suggest a potential role of familial factors related to both MI and SD in PCA. Stronger findings for a familial patterning of PCA were noted for early onset disease in cases and their relatives. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

Browse | Search : All Pubs | Next