Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Stern, Novak, Harlow, and colleagues say compensation due Californians forcibly sterilized under eugenics laws

Burgard and Seelye find job insecurity linked to psychological distress among workers in later years

Former PSC trainee Jay Borchert parlays past incarceration and doctoral degree into pursuing better treatment of inmates

More News

Highlights

Savolainen wins Outstanding Contribution Award for study of how employment affects recidivism among past criminal offenders

Giving Blueday at ISR focuses on investing in the next generation of social scientists

Pfeffer and Schoeni cover the economic and social dimensions of wealth inequality in this special issue

PRB Policy Communication Training Program for PhD students in demography, reproductive health, population health

More Highlights

Next Brown Bag

Mon, Jan 23, 2017 at noon:
H. Luke Shaefer

Piecewise Constant Cross-Ratio Estimation for Association of Age at a Marker Event and Age at Menopause

Publication Abstract

Nan, B., X.H. Lin, L.D. Lisabeth, and Sioban D. Harlow. 2006. "Piecewise Constant Cross-Ratio Estimation for Association of Age at a Marker Event and Age at Menopause." Journal of the American Statistical Association, 101(473): 65-77.

A question of significant interest in female reproductive aging is to identify bleeding criteria for menopausal transition. Although various bleeding criteria, or markers, have been proposed for menopausal transition, their validity has not been adequately examined. The Tremin Trust data were collected from a long-term cohort study that followed a group of women throughout their whole reproductive life. Such data provide a unique opportunity for evaluating the utility of a bleeding criterion-based marker event by assessing the association between age at onset of the bleeding marker and age at onset of menopause. Formal statistical analysis of this dependence is challenged by the facts that both the marker event and menopause are subject to right-censoring and that their association depends on age at the marker event. We propose using the cross-ratio to measure their dependence by assuming the cross-ratio to be a piecewise constant function of age at onset of the marker event. We propose two estimation procedures, the direct two-stage method and the sequential two-stage method, extending the latter to allow for covariates in marginal survival functions. We apply the proposed methods to the analysis of the Tremin Trust data and evaluate their performance using simulations.

DOI:10.1198/016214505000000934 (Full Text)

Browse | Search : All Pubs | Next