Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Bloomberg cites MTF data in story on CDC's anti-smoking ads for e-cigarettes

Bound says notion that foreign students are displacing U.S. students "isn't right"

Prescott says online option for access to court system can help equalize justice

Highlights

U-M ranked #1 in Sociology of Population by USN&WR's "Best Graduate Schools"

PAA 2015 Annual Meeting: Preliminary program and list of UM participants

ISR addition wins LEED Gold Certification

PSC Fall 2014 Newsletter now available

Next Brown Bag

Mon, March 23
Lundberg, State Care of the Elderly & Labor Supply of Adult Children

Cortisol Levels and Very Early Pregnancy Loss in Humans

Publication Abstract

Nepomnaschy, P.A., K.B. Welch, D.S. McDonnell, Bobbi Low, B.I. Strassmann, and B.G. England. 2006. "Cortisol Levels and Very Early Pregnancy Loss in Humans." Proceedings of the National Academy of Sciences of the United States of America, 103(10): 3938-3942.

Maternal stress is commonly cited as an important risk factor for spontaneous abortion. For humans, however, there is little physiological evidence linking miscarriage to stress. This lack of evidence may be attributable to a paucity of research on maternal stress during the earliest gestational stages. Most human studies have focused on "clinical" pregnancy (>6 weeks after the last menstrual period). The majority of miscarriages, however, occur earlier, within the first 3 weeks after conception (approximate to 5 weeks after the last menstrual period). Studies focused on clinical pregnancy thus miss the most critical period for pregnancy continuance. We examined the association between miscarriage and levels of maternal urinary cortisol during the first 3 weeks after conception. Pregnancies characterized by increased maternal cortisol during this period (within participant analyses) were more likely to result in spontaneous abortion (P < 0.05). This evidence links increased levels in this stress marker with a higher risk of early pregnancy loss in humans.

DOI:10.1073/pnas.0511183103 (Full Text)

Browse | Search : All Pubs | Next