Monday, Dec 9
Sharon Kardia: Genomics in the Health & Retirement Study
Zucker, R.A., M.M. Wong, D.B. Clark, K.E. Leonard, John E. Schulenberg, J.R. Cornelius, H.E. Fitzgerald, G.G. Homish, A. Merline, J.T. Nigg, Patrick M. O'Malley, and L.I. Puttler. 2006. "Predicting Risky Drinking Outcomes Longitudinally: What Kind of Advance Notice Can We Get?" Alcoholism - Clinical and Experimental Research, 30(20): 243-252.
This paper summarizes the proceedings ora symposium presented at the 2005 Research Society on Alcoholism meeting in Santa Barbara, California, that spans the interval from toddlerhood to early middle adulthood and addresses questions about how Far ahead developmentally we can anticipate alcohol problems and related substance use disorder and how such work informs our understanding of the Causes and course of alcohol problems and alcohol use disorder. The context of these questions both historically and developmentally is set by Robert Zucker in an introductory section. Next, Maria Wong and colleagues describe the developmental trajectories of behavioral and affective control front preschool to early adolescence in a high risk for alcoholism longitudinal study and demonstrate their ability to predict alcohol drug outcomes in adolescence. Duncan Clark and Jack Cornelius follow with a report on the predicitive utility of parental disruptive behavior disorders in predicting onset of alcohol problems in their adolescent offspring in late adolescence. Next, Kenneth Leonard and Gregory Homish report on adult development study findings relating baseline individual, spouse, and peer network drinking indicators at marriage onset that distinguish different patterns of stability and change in alcohol problems over the first 2 years of marriage. In the final paper, John Schulenberg and colleagues, utilizing national panel data from the Monitoring the Future Study, which cover the 18- to 35-year age span, show how trajectories of alcohol use in early adulthood predict differential alcohol abuse and dependence Outcomes at age 35. Finally, Robert Zucker examines the degree to which the Core symposium questions are answered and comments on next step research and clinical practice changes that are called for by these findings.
PMCID: PMC1761127. (Pub Med Central)