Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

ISR's Scott Page says diverse teams produce optimal results

Bound, Geronimus, et al. find estimates of decreasing longevity among low-SES whites sensitive to measures and interpretations

Thompson casts doubt on the rehabilitative intentions of prison labor

More News

Highlights

Seefeldt discusses her book Abandoned Families, Wed, March 29, 4 PM, Annenberg Auditorium

U-M participants at PAA Annual Meeting, April 27-29

Heather Ann Thompson wins Bancroft Prize for History for 'Blood in the Water'

Michigan ranks in USN&WR top-10 grad schools for sociology, public health, labor economics, social policy, social psychology

More Highlights

Next Brown Bag

Mon, April 10, 2017, noon:
Elizabeth Bruch

Reduced low-frequency heart rate variability relates to greater intimal-medial thickness of the carotid wall in two samples

Publication Abstract

Gautier, C., C.L. Stine, J.R. Jennings, K. Sutton-Tyrrell, M.B. Muldoon, T.W. Kamarck, George A. Kaplan, J. Salonen, and S.B. Manuck. 2007. "Reduced low-frequency heart rate variability relates to greater intimal-medial thickness of the carotid wall in two samples." Coronary Artery Disease, 18(2): 97-104.

We investigated the relationship between heart rate variability and preclinical carotid intima-media thickening, a putative index of atherosclerosis. Methods A sample of 350 men and women (mean age 56.8 years) selected for the presence or absence of untreated hypertension was assessed for heart rate variability at rest and separately for carotid intima-media thickness using duplex ultrasonography (Pittsburgh study). Findings from this sample were cross-validated in a subsample of 68 men drawn from the Kuopio Ischemic Heart Disease Risk Factor trial and selected for the presence or absence of angina. Results In both samples, regression analyses, controlling for known risk factors, showed a significant negative relationship between mean carotid intima-media thickness and low-frequency (0.05-0.15 Hz) heart rate variability, but not high-frequency variability. Discussion The mechanism underlying this relationship remains unclear. The absence of difference in high-frequency variation questions any interpretation in terms of vagal function; the difference in low-frequency variation may implicate vessel wall characteristics or decreased sympathetic nervous system influence. Conclusion Decreased amplitude of low-frequency heart rate variability seems associated with a preclinical atherosclerotic index.

DOI:10.1097/MCA.0b013e328011ac01 (Full Text)

Browse | Search : All Pubs | Next