Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Former trainee Herbert says residential squatters may be a good thing

Work by Couper, Farley et al. shows impact of racial composition on neighborhood choice

Thompson details killings and shaping of official narrative in 1971 Attica prison uprising

More News

Highlights

Michigan ranked #12 on Business Insider's list of 50 best American colleges

Frey's new report explores how the changing US electorate could shape the next 5 presidential elections, 2016 to 2032

U-M's Data Science Initiative offers expanded consulting services via CSCAR

Elizabeth Bruch promoted to Associate Professor

Next Brown Bag

PSC Brown Bags
will resume fall 2016

Socioeconomic and Race/Ethnic Patterns in Persistent Infection Burden Among US Adults

Archived Abstract of Former PSC Researcher

Zajacova, Anna, J.B. Dowd, and A.E. Aiello. 2009. "Socioeconomic and Race/Ethnic Patterns in Persistent Infection Burden Among US Adults." Journals of Gerontology A: Biological and Medical Sciences, 64(2): 272-279.

Background. The pathophysiological mechanisms that underlie health disparities by socioeconomic status and race/ ethnicity are poorly understood. Promising new research suggests that the burden of persistent infection may influence adult disease risk and mortality. This article examines how multiple persistent infections cluster within individuals and how this clustering varies by socioeconomic position and race/ ethnicity in U. S. adults. Methods. We analyze data from the National Health and Nutrition Examination Survey III ( N = 19,275) for adults aged 17-90 years. The clustering of infections within individuals is studied using tetrachoric correlations. Multiple indicator multiple cause models are used to analyze the infection burden construct as measured by seropositivity to Helicobacter pylori, cytomegalovirus, herpes simplex virus-1, and hepatitis B, focusing on the burden's distribution by socioeconomic position and race/ethnicity. The results are corroborated using ordered logistic regression for a commonly used count index of individual infections. Results. Seroprevalence of individual persistent infections is positively correlated, suggesting common factors related to exposure or susceptibility. Education, income, and race/ ethnicity are strong and significant independent predictors of infection burden in U. S. adults in all models. Conclusion. The disproportionate burden of persistent infections among disadvantaged groups across all ages may be one biologic pathway by which low socioeconomic position is related to increased rates of morbidity and mortality in the United States.

PMCID: PMC2655034. (Pub Med Central)

Licensed Access Link

Country of focus: United States of America.

Browse | Search : All Pubs | Next