Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Attempted suicides among U.S. soldiers often occur before or soon after deployment

Shaefer and Edin's book ($2 a Day) cited in piece on political debate over plight of impoverished Americans

Eisenberg tracks factors affecting both mental health and athletic/academic performance among college athletes

Highlights

Elizabeth Bruch promoted to Associate Professor

Susan Murphy elected to the National Academy of Sciences

Maggie Levenstein named director of ISR's Inter-university Consortium for Political and Social Research

Arline Geronimus receives 2016 Harold R. Johnson Diversity Service Award

Next Brown Bag

PSC Brown Bags
will resume fall 2016

Developing multicomponent interventions using fractional factorial designs

Publication Abstract

Chakraborty, Bibhas, Linda M. Collins, Victor J. Strecher, and Susan A. Murphy. 2009. "Developing multicomponent interventions using fractional factorial designs." Statistics in Medicine, 28(21): 2687-2708.

Multicomponent interventions composed of behavioral, delivery, or implementation factors in addition to medications are becoming increasingly common in health sciences. A natural experimental approach to developing and refining such multicomponent interventions is to start with a large number of potential components and screen out the least active ones. Factorial designs can be used efficiently in this endeavor. We address common criticisms and misconceptions regarding the use of factorial designs in these screening studies. We also provide an operationalization of screening studies. As an example, we consider the use of a screening study in the development of a multicomponent smoking cessation intervention. Simulation results are provided to support the discussions.

DOI:10.1002/sim.3643 (Full Text)

PMCID: PMC2746448. (Pub Med Central)

Country of focus: United States of America.

Browse | Search : All Pubs | Next