Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Lam looks at population and development in next 15 years in UN commission keynote address

Mitchell et al. find harsh family environments may magnify disadvantage via impact on 'genetic architecture'

Frey says Arizona's political paradoxes explained in part by demography

Highlights

2014 PAA Annual Meeting, May 1-3, Boston

PSC newsletter spring 2014 issue now available

Raghunathan appointed director of Survey Research Center

Kusunoki wins faculty seed grant award from Institute for Research on Women and Gender

Next Brown Bag


PSC Brown Bags will return in the fall

Developing multicomponent interventions using fractional factorial designs

Publication Abstract

Chakraborty, Bibhas, Linda M. Collins, Victor J. Strecher, and Susan A. Murphy. 2009. "Developing multicomponent interventions using fractional factorial designs." Statistics in Medicine, 28(21): 2687-2708.

Multicomponent interventions composed of behavioral, delivery, or implementation factors in addition to medications are becoming increasingly common in health sciences. A natural experimental approach to developing and refining such multicomponent interventions is to start with a large number of potential components and screen out the least active ones. Factorial designs can be used efficiently in this endeavor. We address common criticisms and misconceptions regarding the use of factorial designs in these screening studies. We also provide an operationalization of screening studies. As an example, we consider the use of a screening study in the development of a multicomponent smoking cessation intervention. Simulation results are provided to support the discussions.

DOI:10.1002/sim.3643 (Full Text)

PMCID: PMC2746448. (Pub Med Central)

Country of focus: United States.

Browse | Search : All Pubs | Next