PSC In The News
Geronimus discusses causes, potential solutions to racial disparities in infant mortality
Kalousova and Burgard find credit card debt increases likelihood of foregoing medical care
Highlights
Trainees Nelson Saldaña, Sarah Seelye and Ellen Compernolle awarded PSC grants
Arline Geronimus wins Excellence in Research Award from School of Public Health
Yu Xie to give DBASSE's David Lecture April 30, 2013 on "Is American Science in Decline?"
U-M grad programs do well in latest USN&WR "Best" rankings
Back in September
Follow us Developing multicomponent interventions using fractional factorial designs
Chakraborty, Bibhas, Linda M. Collins, Victor J. Strecher, and Susan A. Murphy. 2009. "Developing multicomponent interventions using fractional factorial designs." Statistics in Medicine, 28(21): 2687-2708.
Multicomponent interventions composed of behavioral, delivery, or implementation factors in addition to medications are becoming increasingly common in health sciences. A natural experimental approach to developing and refining such multicomponent interventions is to start with a large number of potential components and screen out the least active ones. Factorial designs can be used efficiently in this endeavor. We address common criticisms and misconceptions regarding the use of factorial designs in these screening studies. We also provide an operationalization of screening studies. As an example, we consider the use of a screening study in the development of a multicomponent smoking cessation intervention. Simulation results are provided to support the discussions.
DOI:10.1002/sim.3643 (Full Text)
PMCID: PMC2746448. (Pub Med Central)
Country of focus: United States.
Browse | Search : All Pubs | Next