Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Shaefer says drop child tax credit in favor of universal, direct investment in American children

Buchmueller breaks down partisan views on Obamacare

ISR's Conrad says mobile phone polling faces non-response bias

More News


Gonzalez, Alter, and Dinov win NSF "Big Data Spokes" award for neuroscience network

Post-doc Melanie Wasserman wins dissertation award from Upjohn Institute

ISR kicks off DE&I initiative with lunchtime presentation: Oct 13, noon, 1430 ISR Thompson

U-M ranked #4 in USN&WR's top public universities

More Highlights

Next Brown Bag

Mon, Oct 24 at noon:
Academic innovation & the global public research university, James Hilton

Workshop on Immunizations in Older Adults: Identifying Future Research Agendas

Archived Abstract of Former PSC Researcher

High, K.P., R.T. D'Aquila, R.A. Fuldner, D.N. Gerding, Jeffrey Halter, L. Haynes, W.R. Hazzard, L.A. Jackson, E. Janoff, M.J. Levin, S.G. Nayfield, K.L. Nichol, M. Prabhudas, H.K. Talbot, C.P. Clayton, R. Henderson, C.M. Scott, E.D. Tarver, N.F. Woolard, and K.E. Schmader. 2010. "Workshop on Immunizations in Older Adults: Identifying Future Research Agendas." Journal of the American Geriatrics Society, 58(4): 765-776.

Goals for immunization in older adults may differ from those in young adults and children, in whom complete prevention of disease is the objective. Often, reduced hospitalization and death but also averting exacerbation of underlying chronic illness, functional decline, and frailty are important goals in the older age group. Because of the effect of age on dendritic cell function, T cell-mediated immune suppression, reduced proliferative capacity of T cells, and other immune responses, the efficacy of vaccines often wanes with advanced age. This article summarizes the discussion and proceedings of a workshop organized by the Association of Specialty Professors, the Infectious Diseases Society of America, the American Geriatrics Society, the National Institute on Aging, and the National Institute of Allergy and Infectious Diseases. Leading researchers and clinicians in the fields of immunology, epidemiology, infectious diseases, geriatrics, and gerontology reviewed the current status of vaccines in older adults, identified knowledge gaps, and suggest priority areas for future research. The goal of the workshop was to identify what is known about immunizations (efficacy, effect, and current schedule) in older adults and to recommend priorities for future research. Investigation in the areas identified has the potential to enhance understanding of the immune process in aging individuals, inform vaccine development, and lead to more-effective strategies to reduce the risk of vaccine-preventable illness in older adults.

DOI:10.1111/j.1532-5415.2010.02772.x (Full Text)

Country of focus: United States of America.

Browse | Search : All Pubs | Next