Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Stafford says exiting down stock market worsened position of low-income households

Bailey's work cited on growing income disparities in college enrollment and graduation

Murphy says mobile sensor data will allow adaptive interventions for maximizing healthy outcomes

Highlights

PSC Fall 2014 Newsletter now available

Martha Bailey and Nicolas Duquette win Cole Prize for article on War on Poverty

Michigan's graduate sociology program tied for 4th with Stanford in USN&WR rankings

Jeff Morenoff makes Reuters' Highly Cited Researchers list for 2014

Next Brown Bag

Monday, Nov 3
Melvin Stephens, Estimating Program Benefits

Informing sequential clinical decision-making through reinforcement learning: an empirical study

Publication Abstract

Shortreed, Susan M., Eric Laber, Daniel J. Lizotte, T. Scott Stroup, Joelle Pineau , and Susan A. Murphy. 2011. "Informing sequential clinical decision-making through reinforcement learning: an empirical study." Machine Learning, 84(1-2): 109-136.

This paper highlights the role that reinforcement learning can play in the optimization of treatment policies for chronic illnesses. Before applying any off-the-shelf reinforcement learning methods in this setting, we must first tackle a number of challenges. We outline some of these challenges and present methods for overcoming them. First, we describe a multiple imputation approach to overcome the problem of missing data. Second, we discuss the use of function approximation in the context of a highly variable observation set. Finally, we discuss approaches to summarizing the evidence in the data for recommending a particular action and quantifying the uncertainty around the Q-function of the recommended policy. We present the results of applying these methods to real clinical trial data of patients with schizophrenia.

DOI:10.1007/s10994-010-5229-0 (Full Text)

PMCID: PMC3143507. (Pub Med Central)

Country of focus: United States of America.

Browse | Search : All Pubs | Next