Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Detroit Mayor challenges U-M to analyze root causes, patterns of murders in city

Lam on what helps and hurts in world-wide youth unemployment

Buchmueller says must-access program curbs doctor-shopping for opioids

More News

Highlights

Bailey, Eisenberg , and Fomby promoted at PSC

Former PSC trainee Eric Chyn wins PAA's Dorothy S. Thomas Award for best paper

Celebrating departing PSC trainees

Bloome finds children raised outside stable 2-parent families more likely to become low-income adults, regardless of parents' income

More Highlights

Peripheral Vascular Disease and Peripheral Neuropathy in Individuals With Cardiometabolic Clustering and Obesity National Health and Nutrition Examination Survey 2001-2004

Publication Abstract

Ylitalo, K.R., M. Sowers, and Steven Heeringa. 2011. "Peripheral Vascular Disease and Peripheral Neuropathy in Individuals With Cardiometabolic Clustering and Obesity National Health and Nutrition Examination Survey 2001-2004." Diabetes Care, 34(7): 1642-1647.

OBJECTIVE-Two lower-extremity diseases (LEDs), including peripheral neuropathy and peripheral vascular disease (PVC), are leading causes of disability in the U.S. Although LEDs can be complications of diabetes, their prevelances and risk factors apart from diabetes are poorly described. This study describes the prevalence of LEDs and examines the association of obesity and cardiometabolic clustering in a population-based sample. RESEARCH DESIGN AND METHODS-Adults aged >= 40 years (n = 2,514) were evaluated in the 2001-2004 National Health and Nutrition Examination Survey for clustering of two or more cardiometabolic characteristics, including elevated triglycerides or plasma glucose, low HDL cholesterol levels, increased waist circumference, or hypertension. Clustering was combined with BM1 (dichotomized at >= 30 kg/m(2)) to generate three groups: obese (with or without clustering); nonobese with clustering; and nonobese without clustering. Multivariate logistic regression procedures incorporated the complex survey sampling design. RESULTS-Overall, 9.0% of individuals had peripheral neuropathy alone, 8.5% had PVD alone, and 2.4% had both LEDs. The obese group was more likely to have peripheral neuropathy (odds ratio 2.20 [95% Cl 1.43-3.39]), PVD (3.10 [1.84-5.22]), and both LEDs (6.91 [2.64-18.06]) compared with nonobese subjects without clustering. Within the nonobese group, clustering increased the odds of peripheral neuropathy (1.50 [1.00-2.25]) and PVD (2.48 [1.38-4.44]) compared with no clustering. CONCLUSIONS-Obesity and clustering markedly increased the likelihood of LEDs in this sample and identified a group for whom preventive activities may reduce the risk of future disability.

DOI:10.2337/dc10-2150 (Full Text)

PMCID: PMC3120210. (Pub Med Central)

Country of focus: United States of America.

Browse | Search : All Pubs | Next