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Thompson says US prison population is 'staggeringly high' at about 1.5 million, despite 2% drop for 2015

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NIH funding opportunity: Etiology of Health Disparities and Health Advantages among Immigrant Populations (R01 and R21), open Jan 2017

Russell Sage 2-week workshop on social science genomics, June 11-23, 2017, Santa Barbara

2017 PAA Annual Meeting, April 27-29, Chicago

U-M presents Amy Goodman, Issa Rae, and Shaun King in celebration of MLK

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Mon, Jan 23, 2017 at noon:
Decline of cash assistance and child well-being, Luke Shaefer

A “SMART” Design for Building Individualized Treatment Sequences

Publication Abstract

Lei, H., I. Nahum-Shani, K. Lynch, D. Oslin, and Susan A. Murphy. 2012. "A “SMART” Design for Building Individualized Treatment Sequences." Annual Review of Clinical Psychology, 8: 21-48.

Interventions often involve a sequence of decisions. For example, clinicians frequently adapt the intervention to an individual's outcomes. Altering the intensity and type of intervention over time is crucial for many reasons, such as to obtain improvement if the individual is not responding or to reduce costs and burden when intensive treatment is no longer necessary. Adaptive interventions utilize individual variables (severity, preferences) to adapt the intervention and then dynamically utilize individual outcomes (response to treatment, adherence) to readapt the intervention. The Sequential Multiple Assignment Randomized Trial (SMART) provides high-quality data that can be used to construct adaptive interventions. We review the SMART and highlight its advantages in constructing and revising adaptive interventions as compared to alternative experimental designs. Selected examples of SMART studies are described and compared. A data analysis method is provided and illustrated using data from the Extending Treatment Effectiveness of Naltrexone SMART study.

DOI:10.1146/annurev-clinpsy-032511-143152 (Full Text)

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