Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Thompson says criminal justice policies led to creation of prison gangs like Aryan Brotherhood

Schmitz finds job loss before retirement age contributes to weight gain, especially in men

Kimball says Fed should get comfortable with "backtracking"

Highlights

Overview of Michigan's advanced research computing resources, Monday, June 27, 9-10:30 am, BSRB - Kahn Auditorium

U-M's Data Science Initiative offers expanded consulting services via CSCAR

Elizabeth Bruch promoted to Associate Professor

Susan Murphy elected to the National Academy of Sciences

Next Brown Bag

PSC Brown Bags
will resume fall 2016

Disability in Basic and Instrumental Activities of Daily Living is Associated with Faster Rate of Decline in Cognitive Function of Older Adults

Publication Abstract

Rajan, Kumar B., Liesi E. Hebert, Paul A. Scherr, Carlos Mendes de Leon, and Denis A. Evans. 2013. "Disability in Basic and Instrumental Activities of Daily Living is Associated with Faster Rate of Decline in Cognitive Function of Older Adults." Journals of Gerontology A: Biological and Medical Sciences, 68(5): 624-630.

Background. The purpose of this study is to examine whether physical disability is associated with faster rate of decline in cognitive function.

Methods. A longitudinal population-based cohort of 6,678 initially nondisabled older adults from a biracial urban community was interviewed at 3-year intervals from 1993 to 2012. Cognitive function was assessed using a standardized global cognitive score, and physical disabilities using activities of daily living (ADL) and instrumental activities of daily living (IADL).

Results. During the follow-up period, 2,450 of 6,678 participants (37%) developed ADL and 2,069 of 4,287 participants (48%) developed IADL disability. After adjusting for demographic and physiologic confounders, cognitive function declined a mean of 0.048 unit per year before ADL disability and 0.047 unit per year before IADL disability. In comparison, the rate of cognitive decline accelerated further by 0.076 unit per year (156% increase) after ADL disability and 0.054 unit per year (115% increase) after IADL disability. Severity of ADL and IADL disabilities were also associated with faster cognitive decline following disability.

Conclusions. In old age, cognitive function declines substantially faster following physical disability even after controlling for demographic and physiologic characteristics of participants.

DOI:10.1093/gerona/gls208 (Full Text)

PMCID: PMC3693599. (Pub Med Central)

Browse | Search : All Pubs | Next