Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Work by Bailey and Dynarski cited in NYT piece on income inequality

Pfeffer says housing bubble masked decade-long growth in household net worth inequality

House, Burgard, Schoeni et al find that unemployment and recession have contrasting effects on mortality risk

Highlights

Jeff Morenoff makes Reuters' Highly Cited Researchers list for 2014

Susan Murphy named Distinguished University Professor

Sarah Burgard and former PSC trainee Jennifer Ailshire win ASA award for paper

James Jackson to be appointed to NSF's National Science Board

Next Brown Bag


PSC Brown Bags will return in the fall

Posttraumatic Stress Disorder Across Two Generations: Concordance and Mechanisms in a Population-Based Sample

Archived Abstract of Former PSC Researcher

Roberts, Andrea L., Sandro Galea, S. Bryn Austin, Magdalena Cerda, Rosalind J. Wright, Janet W. Edwards, and Karestan C. Koenen. 2012. "Posttraumatic Stress Disorder Across Two Generations: Concordance and Mechanisms in a Population-Based Sample." Biological Psychiatry, 72(6): 505-511.

Background: Research conducted using small samples of persons exposed to extreme stressors has documented an association between parental and offspring posttraumatic stress disorder (PTSD), but it is unknown whether this association exists in the general population and whether trauma exposure mediates this association. We sought to determine whether mothers' posttraumatic stress symptoms were associated with PTSD in their young adult children and whether this association was mediated by higher trauma exposure in children of women with PTSD.

Methods: Using data from a cohort of mothers (n = 6924) and a cohort of their children (n = 8453), we calculated risk ratios (RR) for child's PTSD and examined mediation by trauma exposure.

Results: Mother's lifetime posttraumatic stress symptoms were associated with child's PTSD in dose-response fashion (mother's 1-3 symptoms, child's RR = 1.2; mother's 4-5 symptoms, RR = 1.3; mother's 6-7 symptoms, RR = 1.6, compared with children of mothers with no symptoms, p < .001 for each). Mother's lifetime symptoms were also associated with child's trauma exposure in dose-response fashion. Elevated exposure to trauma substantially mediated elevated risk for PTSD in children of women with symptoms (mediation proportion, 74%, p < .001).

Conclusions: Intergenerational association of PTSD is clearly present in a large population-based sample. Children of women who had PTSD were more likely than children of women without PTSD to experience traumatic events; this suggests, in part, why the disorder is associated across generations. Health care providers who treat mothers with PTSD should be aware of the higher risk for trauma exposure and PTSD in their children.

DOI:10.1016/j.biopsych.2012.03.020 (Full Text)

PMCID: PMC3412195. (Pub Med Central)

Browse | Search : All Pubs | Next