Home > Publications . Search All . Browse All . Country . Browse PSC Pubs . PSC Report Series

PSC In The News

RSS Feed icon

Starr's findings account for some of the 19% black-white gap in federal sentencing

Frey says suburbs are aging, cities draw millennials

Pfeffer comments on Fed report that reveals 20-year decline in net worth among American families

More News

Highlights

U-M's campus climate survey results discussed in CHE story

U-M honors James Jackson's groundbreaking work on how race impacts the health of black Americans

U-M is the only public and non-coastal university on Forbes' top-10 list for billionaire production

ASA President Bonilla-Silva takes exception with Chief Justice Roberts' 'gobbledygook' jab

More Highlights

Next Brown Bag

Mon, Jan 22, 2018, noon: Narayan Sastry

Amount of Bone Loss in Relation to Time around the Final Menstrual Period and Follicle-Stimulating Hormone Staging of the Transmenopause

Publication Abstract

Sowers, M.R., H.Y. Zheng, M.L. Jannausch, D. McConnell, B. Nan, Sioban D. Harlow, and J.F. Randolph. 2010. "Amount of Bone Loss in Relation to Time around the Final Menstrual Period and Follicle-Stimulating Hormone Staging of the Transmenopause." Journal of Clinical Endocrinology and Metabolism, 95(5): 2155-2162.

Background and Objective: The objective of the study was to describe bone loss rates across the transmenopause related to FSH staging and the final menstrual period (FMP). Design and Setting: This was a population-based cohort of 629 women (baseline age 24-44 yr) with annual data points over 15 yr. Measurements: Measures were bone mineral density (BMD), FSH to define four FSH stages, and menstrual bleeding cessation to define the FMP. Bone loss rates were reported by obesity status. Results: Annualized rates of lumbar spine bone loss began in FSH stage 3, which occurs approximately 2 yr prior to the FMP (1.67%/yr); bone loss continued into FSH stage 4 (1.21%/yr). Mean spine BMD in FSH stage 4 was 6.4% less than spine BMD value in FSH stage 1. Annualized rates of femoral neck (FN) bone loss began in FSH stage 3 (0.55%/ yr) and continued into FSH stage 4 (0.72%/yr). The FN difference between mean values in FSH stage 1 and FSH stage 4 was 5%. Annualized rates of spine bone loss in the 2 yr prior to the FMP were 1.7%/yr, 3.3%/yr in the 2 yr after the FMP, and 1.1%/yr in the 2- to 7-yr period after the FMP. Nonobese women had lower BMD levels and greater bone loss rates. Conclusions: Spine and FN bone loss accelerates in FSH stage 3. Bone loss also began to accelerate 2 yr before the FMP with the greatest loss occurring in the 2 yr after the FMP. Bone loss rates in both spine and FN BMD were greater in nonobese women than obese women. (J Clin Endocrinol Metab 95: 2155-2162, 2010)

DOI:10.1210/jc.2009-0659 (Full Text)

PMCID: PMC2869543. (Pub Med Central)

Country of focus: United States of America.

Browse | Search : All Pubs | Next