Edward Norton

Center to Accelerate Population Research in Alzheimer's (CAPRA)

Research Project Description
Julie P W Bynum, Geoffrey J. Hoffman, Chiang-Hua Chang, Deborah Levine, Kenneth M. Langa, Matthew Allen Davis, Elham Mahmoudi, Edward Norton, Donovan T. Maust, Antoinette Bartolotta Coe

The population of Americans with Alzheimer's disease and related dementias (AD/ADRD) is expected to more than double by 2040. With few effective treatments either to prevent the disease or slow its progression, we are currently limited to managing established disease and avoiding further negative outcomes, at a cost of $100 billion per year.2 The National Alzheimer's Project Act (NAPA) was passed with the goal of reducing the burden of AD/ADRD on not just the person with dementia, but on all of society including its social, economic, and health system effects. There are large gaps in our knowledge about how policy makers, public health and healthcare practitioners, and communities can best prepare and respond to the broad population effects of AD/ADRD with or without a cure. The proposed Center to Accelerate Population Research in Alzheimer's (CAPRA) will be focused on science that informs government and healthcare organization actions to address the negative impacts of dementia on health and financial wellbeing of individuals and the population. Our focus on public policy and healthcare falls into four inter-related themes: 1) healthcare delivery and policy impact on outcomes and quality of care for persons with dementia, 2) diffusion of new technologies, 3) disparities in quality and access to care, and 4) innovative applications of population data that inform allocation of resources and program development. The CAPRA leadership team is uniquely positioned to leverage its own expertise across these themes and the depth of institutional expertise at the University of Michigan across health services, economic, and population research. The over-riding objective of the Center is to enable and expand multidisciplinary research by current and future leaders in the study of delivery, economics, and policies that will reduce the burden of AD/ADRD locally, nationally, and internationally. To do so, the Center will provide an ?on-ramp? for early and established investigators transitioning into AD/ADRD research by providing access to established investigators in the field, pilot funding, and methods and tools specific to AD/ADRD for secondary analysis of data sets. We will accelerate investigator ability to apply these tools by providing training using contemporary, asynchronous didactic approaches as well as networks of investigators with whom to collaborate and from whom to learn. The research that emanates from this new center will have real world implications for payers and policymakers as they struggle with designing effective policies to improve outcomes for the growing population with or at risk for AD/ADRD.

National Institute on Aging

Funding Period: 8/1/2020 to 6/30/2025

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